Non-Surgical Knee Pain Relief in Pittsburgh – Regenexx® Procedures
Avoid invasive surgery. Regenexx® Pittsburgh offers advanced, image-guided injections using your body’s own repair cells to help reduce knee pain and improve mobility.
- Board-Certified Physician On-Site
- Regenexx Network Provider
- Backed by National Patient Registry Data
- Serving Pittsburgh & Surrounding Communities
Why Regenexx May Be a Better First Step Than Surgery
Many knee injuries and chronic conditions don’t require immediate surgery. Regenexx Pittsburgh offers precise, non-surgical procedures performed by a musculoskeletal expert — often with minimal downtime and faster recovery compared to traditional options.
Uses Your Body’s Own Repair Cells — Bone marrow concentrate or PRP
Performed by a Regenexx-Certified Orthopedic Physician
Convenient Pittsburgh Location
Treatments Tailored to Your Imaging & Diagnosis
Treatments Tailored to Your Imaging & Diagnosis
Outcomes Tracked in a National Registry of Over 40,000 Procedures
Call Our Office
(412) 963-6480
Conditions We Commonly Treat with Regenexx
Regenexx Pittsburgh evaluates and treats a wide range of orthopedic knee conditions for patients throughout Fox Chapel, Aspinwall, Highland Park, and nearby areas.
Knee Osteoarthritis
Degeneration of cartilage causing joint stiffness and pain — common in aging adults.
Meniscus Tears
Tears from wear or trauma that limit motion and may lead to unnecessary surgical removal.
Not sure if your condition qualifies?
Complete the Candidate form and we’ll help you figure out your next step.
How Regenexx Procedures Work
Regenexx uses your body’s own components — either blood or bone marrow — to support tissue repair. All procedures are performed under precise image guidance to target the affected area and avoid surrounding structures.
01
Regenexx-SD – Bone Marrow Concentrate
Collected from the back of the hip, processed to concentrate healing cells, and re-injected into the knee. Commonly used for arthritis, ligament injuries, and moderate-to-severe cases.
02
Regenexx-SCP – Advanced Platelet Procedures (PRP)
Drawn from your blood and processed to create high-purity, high-concentration platelet-rich plasma. Often used for early arthritis, overuse injuries, or tendon issues.
FDA Disclaimer
Regenexx procedures comply with FDA regulations for autologous use and minimal manipulation but are not FDA-approved drugs or devices. All procedures are physician-directed and performed under medical supervision.
Are Regenexx Procedures Safe?
Risks & Safety Considerations: Regenexx procedures are minimally invasive, but like any medical procedure, they carry potential risks. These may include:
- Soreness or swelling at the injection site
- Mild bruising or stiffness
- Low risk of infection or bleeding
- Rare complications depending on individual health
Your Regenexx physician will review all risks during your consultation and tailor a plan to minimize them.
What Results Are Patients Reporting?
Based on data from the Regenexx national patient registry for knee procedures (3,585 patients as of March 2021):
Knee Function Improvement
55% → 74% (Functional Rating Index)
Pain Reduction
4.2 → 2.3/10 (Numeric Pain Scale)
Overall Joint Improvement
37% better just one month after treatment
Individual results may vary. For more details, visit Regenexx Outcome Data.
Frequently Asked Questions
Are Regenexx procedures covered by insurance?
Is this a stem cell procedure?
Regenexx uses bone marrow concentrate, which includes naturally occurring stem cells. These are not manipulated or expanded in a lab, and all protocols follow FDA guidance.
How long does the procedure take?
Most procedures take 60–90 minutes and are done in-office.
How do I know if I’m a candidate?
Complete our short form — our physician will review your case and contact you with next steps.
Free Resources to Help You Decide
Report: 10 Rarely Discussed Facts About Knee Replacement Surgery
Includes Medicare data, complication rates, and lesser-known risks of common surgical options.
Guide: Understanding Regenexx Knee Procedures
- How each procedure works
- What conditions qualify
- Recovery expectations
- Questions to ask your provider
We’ll never spam you or sell your information.
Who Performs These Procedures?
Dr. Paul S. Lieber
MD – Regenexx Pittsburgh
Dr. Marc Adelsheimer
MD – Regenexx Pittsburgh
Dr. Jesse A. Sally
MD – Regenexx Pittsburgh
Where to Find Regenexx Pittsburgh
Main Clinic
Regenexx Pittsburgh 107 Gamma Dr, Suite 220 Gamma Medical Center Pittsburgh, PA 15238
Call Our Office
(412) 963-6480
Office Hours
Mon–Fri: 8:00AM–4:30PM
Directions & Landmarks:
Located just off Route 28 near Fox Chapel Plaza. Free parking onsite. Easy access from Highland Park, Aspinwall, and O’Hara Township.
McMurray
Regenexx Pittsburgh 451 Valley Brook Rd suite 201 McMurray, PA 15317
Call Our Office
(412) 963-6480
Office Hours
Mon–Fri: 8:00AM–4:30PM
Directions & Landmarks:
Located just off Route 28 near Fox Chapel Plaza. Free parking onsite. Easy access from Highland Park, Aspinwall, and O’Hara Township.
Glossary of Terms
| Term | Definition |
|---|---|
|
Autologous |
Originating from your own body (e.g., blood or marrow) |
|
PRP |
Platelet-Rich Plasma — plasma with concentrated platelets that support healing |
|
BMC |
Bone Marrow Concentrate — marrow cells processed to concentrate healing components |
|
Image-Guided Injection |
Use of ultrasound or fluoroscopy to guide precise needle placement |
